Meta-analysis of transanal vs laparoscopic total mesorectal excision of low rectal cancer: Importance of appropriate patient selection

Table 2 Included studies related data

Ref.	Publication year	Age	Gender	BMI	Neoadjuvant therapy	Tumour stage	Tumour location	Distance of tumour to anal verge
de’Angelis[13]	2015	64.91 ± 10.05 vs 67.16 ± 9.61	66% vs 66%	25.19 ± 3.52 vs 24.53 ± 3.19	100% vs 100%	I: 65.6% vs 56.3%; II: 31.3% vs 40.6%; III: 3.1% vs 3.1%	Low rectum	4 (2.5-5.0) vs 3.7 (2.5-5.0)
Kanso et al[14]	2015	59 ± 11 (32-79) vs 59 ± 11 (33-82)	71% vs 77%	24 ± 4 (17-32) vs 24 ± 4 (15-34)	80% vs 79%	NR	Lower rectum	1.6 ± 0.8 (0-3.5) vs 1.8 ± 0.9 (0-3.5)
Pontallier et al[15]	2016	62 (39-81) vs 62 (35-82)	68% vs 62%	25.5 vs 24.8	79% vs 88%	I: 21% vs 21%; II: 19% vs 14%; III: 60% vs 65%	Low rectum	4 (2-6) vs 4 (2-6)
Marks et al[16]	2016	60 vs 59	NR	25.9 vs 26.4	NR	I: 29.4% vs 23.5%; II: 70.6% vs 76.5%	Low rectum	< 4 vs < 4
Lelong et al[17]	2017	NR	68% vs 58%	24 (18.6-45.0) vs 24.2(17.7-32.7)	88.2% vs 92.1%	I: 17.6% vs 23.7%; II: 70.6% vs 71.0%; III: 11.8% vs 5.3%	Low rectum	NR
Denost et al[18]	2018	64 (39-82) vs 63 (31-90)	74% vs 64%	25.1 (17.3-33.2) vs 25.6 (18.3-38.3)	78% vs 84%	NR	Low rectum	4 (2-6) vs 4 (2-6)
Mege et al[19]	2018	58 ± 14 vs 59 ± 13	68% vs 68%	25 ± 4 vs 25 ± 3	85% vs 85%	I: 29.4% vs 11.8%; II: 67.6% vs 82.3%; III: 43.5% vs 47.8%; IV: 2.9% vs 5.9%	Low rectum	NR
Rubinkiewicz et al[20]	2018	64.3 ± 10.1 vs 60.3 ± 10.2	69% vs 69%	26.10 ± 4.09 vs 27.10 ± 4.71	88.6% vs 88.6%	I: 42.9% vs 45.7%; II: 57.1% vs 54.3%	Low rectum	2.90 ± 1.17 vs 3.19 ± 1.47
Roodbeen et al[21]	2019	62.5 ± 10.7 vs 66.0 ± 9.2	82.9% vs 78%	26.7 ± 1.9 vs 26.1 ± 4.0	43.9% vs 43.9%	I: 22.0% vs 19.5%; II: 36.6% vs 39%; III: 31.7% vs 31.7%; IV: 9.8% vs 9.8%	Low rectum	2.0 (0.0-4.0) vs 1.5 (0.0-3.0)
Rubinkiewicz et al[22]	2019	60 (51-67) vs 64 (58-67)	69% vs 69%	26 (22.8-29.7) vs 26.5 (23.8-30.6)	78.2% vs 82.6%	NR	Low rectum	3(2-4) vs 4 (3-5)
Ren et al[23]	2021	65.78 ± 12.37 vs 67.16 ± 10.03	59.3% vs 56.2%	22.87 ± 2.66 vs 23.05 ± 2.70	71.8% vs 65.6%	I: 34.3% vs 37.5%; II: 28.1% vs 31.2%; III: 31.2% vs 21.8%	Low rectum	5.53 ± 0.98 vs 5.78 ± 0.94
Li et al[24]	2022	55 ± 12 (23-78) vs 56 ± 12 (26-79)	100% vs 100%	23:0 ± 2.9 vs 22:9 ± 3.2	100% vs 100%	NR	Low rectum	3.6 ± 0.9 (2.0-5.0) vs 3.8 ± 0.9 (1.4-5.0)

Transanal total mesorectal excision vs Laparoscopic total mesorectal excision. BMI: Body mass index; NR: Not reported.