Real-time in vivo distal margin selection using confocal laser endomicroscopy in transanal total mesorectal excision for rectal cancer

Table 2 Probe-based confocal laser endomicroscopy diagnostic accuracy considering pathology as the standard reference

	Observer A (real-time interpretation)		Observer B (blinded interpretation)
	%	95%CI	%	95%CI
Sensitivity	90.00	76.34-97.21	87.50	73.20-95.81
Specificity	86.96	73.74-95.06	84.78	71.13-93.66
Accuracy	88.37	79.65-94.28	86.05	76.89-92.58
PPV	85.71	71.46-94.57	83.33	68.64-93.03
NPV	90.91	78.33-97.47	88.64	75.44-96.21
Interobserver agreement	κ = 0.767, standard error = 0.069

CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value.