Assessment of tumor markers CA 19-9, CEA, CA 125, and CA 242 for the early diagnosis and prognosis prediction of gallbladder cancer

Table 3 Association between tumor markers and clinical characteristics

Characteristics	CA 19-9		P value	CA 125		P value	CEA		P value	CA 242		P value
	Normal, n = 131	Elevated, n = 69		Normal, n = 161	Elevated, n = 39		Normal, n = 181	Elevated, n = 19		Normal, n = 119	Elevated,n = 81
Age, yr	49.0 (39.0-59.0)	55.0 (45.0-63.5)	0.009	50.0 (39.0-59.0)	56.0 (50.0-69.0)	0.001	50.0 (40.0-59.5)	56.0 (45.0-65.0)	0.093	48.0 (34.0-56.0)	56.0 (47.5-64.5)	< 0.001
Sex
Male	46 (35.1)	22 (31.9)	0.754	51 (31.7)	17 (43.6)	0.112	62 (34.3)	6 (31.6)	> 0.05	41 (34.5)	27 (33.3)	0.881
Female	85 (64.9)	47 (68.1)		110 (68.3)	22 (56.4)		119 (65.7)	13 (68.4)		78 (65.5)	54 (66.7)
Gallstones
Absent	12 (9.2)	10 (14.5)	0.181	19 (11.8)	3 (7.7)	0.578	21 (11.6)	1 (5.3)	0.701	7 (5.9)	15 (18.5)	0.010
Present	119 (90.8)	59 (85.5)		142 (88.2)	36 (92.3)		160 (88.4)	18 (94.7)		112 (94.1)	66 (81.5)

Data shown as n (%). Test used: χ² test. CA 19-9: Carbohydrate antigen 19-9; CA 125: Carbohydrate antigen 125; CA 242: Carbohydrate antigen 242; CEA: Carcinoembryonic antigen.