Clinical value of extended lymphadenectomy in radical surgery for pancreatic head carcinoma at different T stages

Table 4 General data between extended and standard lymphadenectomy group in pancreatic head carcinoma patients at different T stages

Variables	T1 stage			T2 stage			T3 stage
	ELD group (n = 16)	SLD group (n = 28)	P value	ELD group (n = 51)	SLD group (n = 76)	P value	ELD group (n = 21)	SLD group (n = 24)	P value
Gender (male/female)	10/6	14/14	0.423	32/19	46/30	0.801	9/12	13/11	0.449
Age (yr)	62.8 ± 12.4	64.1 ± 9.7	0.696	64.2 ± 9.8	64.7 ± 10.3	0.801	56.2 ± 10.9	64.8 ± 9.7	0.001
TB (μmol/L)	58.1 (16.8, 107.5)	72.3 (28.1, 149.0)	0.742	80.8 (14.6, 149.3)	60.6 (12.7, 168.7)	0.885	44.4 (13.0, 137.7)	29.4 (10.3, 96.8)	0.285
CA19-9 (U/mL)	115.9 (24.0, 262.8)	92.5 (38.7, 312.5)	0.817	152.7 (53.7, 545.9)	207.0 (43.5, 1058.9)	0.507	180.2 (39.6, 556.4)	424.5 (77.8, 1285.6)	0.270
Intraoperative blood loss (mL)	500 (400, 600)	500 (400, 650)	0.788	500 (400, 800)	600 (400, 800)	0.310	500 (400, 1000)	550 (400, 1000)	0.741
Operation time (h)	10.8 ± 3.5	9.5 ± 2.9	0.194	10.9 ± 2.5	11.3 ± 2.7	0.404	11.9 ± 3.0	11.6 ± 3.2	0.746
Tumor size (cm)	1.7 ± 0.4	1.8 ± 0.3	0.274	3.2 ± 0.5	3.4 ± 0.5	0.193	5.4 ± 1.0	6.1 ± 2.0	0.155
Tumor differentiation (poorly/moderately-highly)	2/14	11/17	0.126	14/37	24/52	0.619	9/12	12/12	0.632
Portal vein invasion (yes/no)	4/12	6/22	0.919	28/23	45/31	0.630	15/6	18/6	0.787
Lymph node metastasis (yes/no)	10/6	15/13	0.565	31/20	55/21	0.171	15/6	23/5	0.587
Retrieved lymph node count	21 (18, 32)	15 (12, 19)	0.004	26 (21, 33)	23 (16, 31)	0.509	25 (15, 40)	20 (15, 30)	0.030
Positive lymph node count	2 (0, 2)	1 (0, 2)	0.373	1 (0, 4)	2 (0, 4)	0.513	1 (0, 3)	4 (1, 5)	0.022
Resection margin (R0/R1)	16/0	28/0	-	48/3	68/8	0.555	19/2	22/2	0.700
Postoperative chemotherapy (yes/no)	6/10	15/13	0.305	29/22	36/40	0.294	13/8	10/14	0.175

ELD: Extended lymphadenectomy; SLD: Standard lymphadenectomy; TB: Total bilirubin; CA19-9: Carbohydrate antigen 199; R: Resection margin.