Routine laboratory parameters in patients with necrotizing pancreatitis by the time of operative pancreatic debridement: Food for thought

doi:10.4240/wjgs.v14.i1.64

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Jan 27, 2022 (publication date) through Jan 24, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jan 27, 2022; 14(1): 64-77
Published online Jan 27, 2022. doi: 10.4240/wjgs.v14.i1.64

Table 2 The dynamic changes of laboratory variables in the survivors with different Length of stay in hospital

Laboratory variable	Post-OPD LOS ≤ 50 d, n = 12	post-OPD LOS ≥ 50 d, n = 31
Hgb (g/L)
Day 1 (A)	111.4 ± 12.1	176.3 ± 31.2^a
Day 3-9 (B)	93.6 ± 8.9	116.4 ± 26.6
Δ (B-A)	-35.5 ± 12.9	-46.4 ± 7.5
Day before OPD (E)	89.4 ± 7.8	83.6 ± 7.2
Δ (E-A)	-22.0 ± 11.4	-79.2 ± 12.0^a
WBC (× 10⁹/L)
Day 1 (A)	9.6 ± 3.9	11.5 ± 1.7
Day 3-9 (B)	16.5 ± 9.8	13.1 ± 4.6
Δ (B-A)	3.6 ± 6.3	-0.6 ± 6.6
Day before OPD (E)	10.1 ± 2.5	13.8 ± 4.7
Δ (E-A)	0.6 ± 2.4	2.4 ± 4.3
PLT (× 10⁹/L)
Day 1 (A)	236.5 ± 57.8	223.5 ± 64.2
Day 3-9 (B)	453.5 ± 58.3	224.0 ± 44.5^a
Δ (B-A)	232.8 ± 50.9	-7.5 ± 57.8^a
Day before OPD (E)	648.0 ± 74.7	360.2 ± 104.8^a
Δ (E-A)	430.5 ± 76.4	181.0 ± 48.7^a
AST (μkat/L)
Day 1 (A)	0.56 ± 0.31	0.99 ± 0.35
Day 3-9 (B)	0.44 ± 0.06	0.72 ± 0.13^a
Δ (B-A)	-0.18 ± 0.27	-0.84 ± 0.41
Day before OPD (E)	0.36 ± 0.11	0.42 ± 0.19
Δ (E-A)	-0.19 ± 0.28	-1.0 ± 1.0
ALT (μkat/L)
Day 1 (A)	0.71 ± 0.52	1.79 ± 1.31
Day 3-9 (B)	0.46 ± 0.18	1.02 ±0.52^a
Δ (B-A)	-0.34 ± 0.43	-1.32 ± 0.84
Day before OPD (E)	0.51 ± 0.22	0.51 ± 0.16
Δ (E-A)	-0.21 ± 0.39	-1.28 ± 1.24
DB (μmol/L)
Day 1 (A)	15.73 ± 19.79	14.95 ± 11.53
Day 3-9 (B)	3.21 ± 0.87	6.78 ± 4.37
Δ (B-A)	-18.5 ± 22.19	-10.02 ± 10.81
Day before OPD (E)	1.72 ± 1.01	2.55 ± 0.74
Δ (E-A)	-14.02 ± 19.79	-12.4 ± 11.53
AML (U/L)
Day 1 (A)	65.8 ± 48.07	56.3 ± 24.47
Day 3-9 (B)	26.62 ± 8.11	38.94 ± 27.03
Δ (B-A)	-32.34 ± 43.11	-17.36 ± 16.55
Day before OPD (E)	21.18 ± 4.85	27.46 ± 16.61
Δ (E-A)	-44.62 ± 47.55	-28.84 ± 41.51

^aP ≤ 0.05 as compared to patients with post-OPD LOS ≤ 50 d. A: Day 1 (on admission); B: Day 3-7; C: Day 12-16; D: Day 21-24; E: Day before the operative pancreatic debridement. ALT: Alanine aminotransferase; AML: α-amylase; AST: Aspartate aminotransferase; DB: Direct bilirubin; Hgb: Hemoglobin; LOS: Length of stay in hospital; OPD: Operative pancreatic debridement; PLT: Total platelets count; WBC: Total white blood cell count.

Citation: Susak YM, Opalchuk K, Tkachenko O, Rudyk M, Skivka L. Routine laboratory parameters in patients with necrotizing pancreatitis by the time of operative pancreatic debridement: Food for thought. World J Gastrointest Surg 2022; 14(1): 64-77
URL: https://www.wjgnet.com/1948-9366/full/v14/i1/64.htm
DOI: https://dx.doi.org/10.4240/wjgs.v14.i1.64