Reappraisal of surgical decision-making in patients with splenic sclerosing angiomatoid nodular transformation: Case series and literature review

Table 2 Comparison of Image characteristics among common splenic tumor

	Tumor	Tumor shape, features, and characteristics	MRI T1	MRI T2	CT/MRI enhancing pattern	Other image characteristics probably aid diagnosis
Benign	SANT	Well-circumscribed, commonly lobulated, solitary mass	Iso-hypointense	Hypointense	Spoke-Wheel pattern; Poor enhancement	PET/CT: Low FDG accumulation
	Hemangioma	Single nodule; multiple nodules; diffuse masses enlarging the spleen	Hypointense	Hyperintense	Homogenous or peripheral enhancement	Mostly small, asymptomatic, and slow growth
	Cyst	Cystic lesion	Hypointense	Hyperintense	No enhancement	Ultrasound: Thin wall, anechoic, peripheral brightly echogenicity, and distal shadows due to wall calcification
Malignant	Systemic lymphoma	Homogenous splenomegaly; Infiltrative miliary lesions (1-5 mm); Multifocal lesions (2-10 cm); Uncommon solitary lesions (7-14 cm)	Isointense	Hypointense	Poor enhancing	Splenomegaly; Splenic infarct; PET: Intense heterogenous FDG activity; Extra-splenic findings: Hepatomegaly, lymphadenopathy
	Primary splenic lymphoma	Solitary mass > uncommonly Splenomegaly	Isointense	Hypointense	Poor enhancing	Central necrosis
	Metastasis	Variously	Iso-hypointense	Hyperintensity	Similar to the primary tumor	PET/CT: FDG-avid tumor; Poorly marginated; Heterogenous

CT: Computed tomography; MRI: Magnetic resonance imaging; PET: Positron emission tomography; FDG: Fluorodeoxyglucose.