Reappraisal of surgical decision-making in patients with splenic sclerosing angiomatoid nodular transformation: Case series and literature review

Table 1 Characteristic of three patients with sclerosing angiomatoid nodular transformation

No.	Age (yr)	Sex	Indication	Symptoms	Size	CT		MRI		PET	Follow up	Surgery
						A phase	V phase	T1/T2	Contrast
1	48	M	Diagnostic splenectomy, for Atypical hemangioma MRI pattern, suspect lymphoma	8 kg loss in 2 yr; left abdominal painFatigue	5.5 cm	Septate enhancement	Mild progressing peripheral enhancement with centrally remained iso-hypodense	Iso-hypodense/iso-hypodense	Heterogenous gradual enhancement and diffusion restriction	Nil	2 mo	Open
2	61	F	Diagnostic splenectomy, for elevated CA19-9, malignancy cannot be rule out	Nil	4.1 cm	Mild enhancement	Mild progressing peripheral enhancement with centrally remained iso-hypodense	Iso-hypodense/hypodense	Mild peripheral enhancement	Nil	6 mo	Laparoscopy
3	52	M	Diagnostic splenectomy, for suspect lymphoma splenic involvement1	Nil	3.5 cm	Peripheral enhancement	Nil	Nil		Diffuse mild hypermetabolism at spleen (2SUVmax = 4.2)	4 mo	Laparoscopy

¹Underlying with B-cell non-Hodgkin lymphoma, Ann Arbor stage IV, IPI score 2, suspected marginal zone lymphoma, status post R-CHOP (VI, 2019/1/7-2019/07/19).

²SUVmax: maximum standardized uptake value.

SUV: Standardized uptake value; CT: Computed tomography; MRI: Magnetic resonance imaging; PET: Positron emission tomography; Non contrast CT: Iso-hypodense.