Efficacy of hybrid endoscopic submucosal dissection with SOUTEN in gastric lesions: An ex vivo porcine model basic study

Table 2 Comparison of treatment outcomes of endoscopic submucosal dissection between two groups

	Hybrid ESD (n = 32)	Conventional ESD (n = 32)	P value
ESD procedure time, min
Median (IQR)	8.3 (6.6-12.0)	16.2 (9.5-20.1)	< 0.001a
En bloc resection, n (%)	32 (100)	32 (100)
Complete resection, n (%)	30 (93.8)	28 (87.5)	0.67
Perforation, n (%)	0 (0)	1 (3.1)	1
Mucosal incision time, min
Median (IQR)	3.5 (2.5-5.5)	4.2 (2.7-5.3)	0.82
Submucosal dissection time, min
Median (IQR)	5.2 (3.7-6.6)	10.4 (7.0-15.1)	< 0.001a
Resected specimen size, mm2
Median (IQR)	254.3 (201-282.6)	247.3 (201.0-254.3)	0.44
Circumferential length, mm
Median (IQR)	56.5 (50.3-59.7)	55.8 (50.3-56.5)	0.49
Mucosal incision speed, mm/min
Median (IQR)	15.3 (10.8-20.1)	13.0 (10.0-20.3)	0.67
Submucosal dissection speed, mm2/min
Median (IQR)	43.7 (34.6-64.6)	23.8 (17.0-30.1)	< 0.001a
Total injection volume, mL
Median (IQR)	8.3 (6.6-12.0)	16.2 (9.5-20.1)	< 0.001a
Injection volume during mucosal incision, mL
Median (IQR)	5.0 (4.5-7.0)	6.0 (4.8-7.6)	0.40
Injection volume during submucosal dissection, mL
Median (IQR)	1.5 (1.0-2.1)	3.0 (2.4-5.6)	< 0.001a

P value was calculated by chi-square test, Fisher’s exact test and Mann-Whitney U test.

^aSignificant value.

ESD: Endoscopic submucosal dissection; IQR: Interquartile range.