Liver resection for hepatocellular carcinoma larger than 10 cm: A multi-institution long-term observational study

Table 5 Comparison of current study with our previous report

	Yeh etal[27]: 1st era	Current study: 2nd era
Number of HCC ≥ 10 cm	211	426
Study period	1982-2001	2002-2015
Study design	Retrospective	Institutional-based cohort with IPTW
Age in yr	47.8 ± 14.3	55.7 ± 14.3
Gender, male %	78%	81%
HBV infection, positive	81.9%	52.8%
HCV infection, positive	11.6%	10.3%
Size in cm	13.9 ± 3.4	13.14 ± 4.95
Surgical mortality at 30-d	4.3%	2.1%
1-yr DFS rate	32.9%	48.5%
3-yr DFS rate	18.8%	36.1%
5-yr DFS rate	12.7%	31.1%
1-yr OS rate	48.1%	75.8%
3-yr OS rate	24.0%	53.3%
5-yr OS rate	16.7%	46.2%

DFS: disease-free survival; HCC: Hepatocellular carcinoma; IPTW: Inverse-probability of treatment weighting; OS: Overall survival.