Could neoadjuvant chemotherapy increase postoperative complication risk of laparoscopic total gastrectomy? A mono-institutional propensity score-matched study in China

Table 3 Surgical indicators in perioperative days between laparoscopic total gastrectomy after neoadjuvant chemotherapy and laparoscopic total gastrectomy group

Variable	NC-LTG group (n = 73)	LTG group (n = 73)	P value
Surgical time, min (mean ± SD)	244.10 ± 48.13	225.74 ± 45.33	0.019
Blood loss, mL (median, IQR)	150 (100-300)	100 (100-200)	0.011
Retrieved lymph nodes, n (mean ± SD)	31.14 ± 11.81	32.21 ± 12.12	0.593
Fist flatus day, d (mean ± SD)	4.25 ± 1.11	4.27 ± 1.10	0.896
R0 resection rate, n (%)	3 (4.1)	3 (4.1)	1.000
Postoperative day, d (median, IQR)	9.0 (7.0-11.0)	8.0 (7.0-11.0)	0.602
Total complication rate, n (%)	15 (20.5)	10 (13.7)	0.272
Clavien-Dindo classification
Grade II
Anastomosis leakage	2	1
Lymphatic leakage	1	2
Abdominal infection	1	0
Ileus	1	0
Anemia	3	1
Pneumonia	1	0
Hypoproteinemia	2	2
Grade III
Deep venous thrombosis	1	0
Anastomosis leakage	0	1
Intestinal leakage	0	1
Seroperitoneum	0	1
Abdominal hemorrhage	0	1
Grade IV
Cerebral infraction	2	0
Grade V
Severe pneumonia	1	0
Severe complication rate, n (%)	4 (5.5)	4 (5.5)	1.000

NC-LTG: Laparoscopic total gastrectomy after neoadjuvant chemotherapy; LTG: Laparoscopic total gastrectomy; IQR: Interquartile range.