Combination of preoperative fibrinogen and D-dimer as a prognostic indicator in pancreatic ductal adenocarcinoma patients undergoing R0 resection

Figure 4 Difference in survival between groups based on preoperative fibrinogen combined with D-dimer indicated by Kaplan-Meier curves. A: Preliminary analysis after subdividing the four groups of enrolled patients (blue line: preoperative fibrinogen concentration > 3.31 g/L and preoperative D-dimer concentration > 0.53 mg/L; green line: preoperative D-dimer concentration > 0.53 mg/L and preoperative fibrinogen concentration ≤ 3.31 g/L; purple line: preoperative fibrinogen concentration > 3.31 g/L and preoperative D-dimer concentration ≤ 0.53 mg/L; and red line: preoperative fibrinogen concentration ≤ 3.31 g/L and preoperative D-dimer concentration ≤ 0.53 mg/L); B: Subgroup analysis of enrolled patients (blue line: preoperative fibrinogen concentration > 3.31 g/L and/or preoperative D-dimer concentration > 0.53 mg/L; and red line: preoperative fibrinogen concentration ≤ 3.31 g/L and preoperative D-dimer concentration ≤ 0.53 mg/L). FIB: Fibrinogen; DD: D-dimer.