Novel roles of lipopolysaccharide and TLR4/NF-κB signaling pathway in inflammatory response to liver injury in Budd-Chiari syndrome

Figure 2 Hepatic mRNA and protein expression levels of lipopolysaccharide and various factors in rats and humans. A: The expression levels of lipopolysaccharide (LPS) in each group; B: TLR4 expression in each group; C: Nuclear factor-kappa B p65 expression in each group; D: Tumor necrosis factor-α expression in each group; E: Interferon-γ expression in each group; F: Interleukin-2 expression in each group; G: Western blot analysis of protein express levels of various factors in the rat liver tissues; H: Levels of LPS and TLR4/NF-κB mediated inflammation-related indicators in the blood samples from human subjects. LPS: Lipopolysaccharide; TLR4: Toll-like receptor 4; NF-κB: Nuclear factor-kappa B; TNF-α: Tumor necrosis factor-α; IL-2: Interleukin-2; IFN-γ: Interferon-γ. ^aP < 0.05 comparisons between subgroups. ^bP < 0.05 comparisons between model subgroups.