Risk of station 12a lymph node metastasis in patients with lower-third gastric cancer

Table 2 Univariate and multivariate analyses of predictive factors for station 12a lymph nodes metastasis

Variables	Univariate analysis			Multivariate analysis1			Multivariate analysis2
	OR	95%CI	P value	OR	95%CI	P value	OR	95%CI	P value
Gender	1.745	0.648-4.700	0.271
Age at surgery	1.076	0.399-2.906	0.885
Lauren classification	1.427	0.549-3.709	0.465
Borrmann type	1.404	0.643-3.066	0.396
Maximum diameter	4.562	1.424-14.619	0.011	2.838	0.743-10.840	0.127	4.012	1.231-13.078	0.021
Examined lymph node count	1.268	0.641-2.510	0.495
pT stage	2.935	1.807-7.924	0.034	1.456	0.389-5.449	0.577	2.055	0.749-5.642	0.162
pN stage	3.336	1.971-5.648	< 0.001	3.322	1.962-5.625	< 0.001
Soft tissue invasion	3.500	1.249-9.804	0.017	1.201	0.350-4.121	0.771	2.912	1.007-8.420	0.048
Perineuronal invasion	0.000	0.000	1.000
Vessel invasion	0.000	0.000	0.999
Surgical options	0.568	0.240-1.343	0.197
BMI	1.400	0.519-3.779	0.507
Adjuvant chemotherapy	2.866	0.789-10.415	0.11
Blood transfusion	0.824	0.174-3.903	0.807

¹Four factors with significance (P < 0.05) in the univariate analysis were included in the multivariate analysis.

²Factors with significance in univariate analysis excluding pN stage were included in the multivariate analysis.

CI: Confidence interval; OR: Odds ratio; BMI: Body mass index.