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©The Author(s) 2021.
World J Gastrointest Surg. Oct 27, 2021; 13(10): 1267-1278
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1267
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1267
Table 3 Descriptive characteristics of patients with immunotherapy for post-transplant hepatocellular carcinoma recurrence
All | Nivolumab | Pembrolizumab | P value | |
Total (%) | 19 | 14 (74) | 5 (26) | |
Rejection (%) | 6 (32) | 5 (36) | 1 (20) | 0.52 |
Early mortality (%) | 5 (26) | 5 (36) | 0 (0) | 0.12 |
Line of systemic therapy | 2 (1-3) | 3 (2-4) | 2 (1-2) | 0.03 |
Tumour PD-L1 positivity (%) | 3/7 (43) | 3/7 (43) | 0/0 (-) | |
Best treatment response (%) | ||||
Complete response | 2 (11) | 0 (0) | 2 (40) | 0.03 |
Partial response | 0 (0) | 0 (0) | 0 (0) | 0.64 |
Stable disease | 2 (11) | 1 (7) | 1 (20) | 0.58 |
Progressive disease | 8 (42) | 7 (50) | 1 (20) | 0.03 |
Progression-free survival | 2.5 ± 1.0 | 1.3 ± 1.1 | 12.4 | 0.004 |
Overall survival | 7.3 ± 2.7 | 4.0 ± 3.4 | 19.2 | 0.006 |
- Citation: Au KP, Chok KSH. Immunotherapy after liver transplantation: Where are we now? World J Gastrointest Surg 2021; 13(10): 1267-1278
- URL: https://www.wjgnet.com/1948-9366/full/v13/i10/1267.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v13.i10.1267