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©The Author(s) 2021.
World J Gastrointest Surg. Oct 27, 2021; 13(10): 1166-1179
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1166
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1166
Ref. | Outcome parameters | LR group | PD group |
Systematic review and meta-analysis | |||
Chok et al[61] (n = 162) | Surgical morbidity; Oncologic outcomes | Better (20.7%); Better DFS (HR 2.07, 95%CI: 1.07–4.01), lower rate of distant metastasis (8.9% vs 25.8%, OR 0.28, 95%CI: 0.13–0.59) | Worse (48.3%) (RR 2.34, 95%CI: 1.61–3.42). Worse: Related to large tumor (≥ 5 cm) (76.0% vs 36.6%, OR 5.49, 95%CI: 1.8–16.76), high mitotic count ≥ 5/50 HPF (33.7% vs 18.5%, OR 2.23, 95%CI: 1.22–4.08), high-risk classification (60.3% vs 32.0%, OR 3.23, 95%CI: 1.65–6.34) and which were located at D2 (80.5% vs 28.6%, OR 10.33, 95%CI: 5.22–20.47) |
Shen et al[62] (n = 623) | Complications; Long term prognosis | Less; Better | More (OR 2.90; 95%CI: 1.90-4.42; P < 0.001); Worse (HR 1.93; 95%CI: 1.39-2.69; P < 0.001); Related to invasion of the D2, higher degree tumor mitosis (> 5/50 HPF) and high-risk classification (P < 0.001) |
Zhou et al[63] (n = 1103) | Surgical outcomes | Better | Worse: Related to higher incidence of mitotic index > 5/50 HPF, high-risk classification, D2 tumor, tumor size, operative duration, intraoperative blood loss, blood transfusion requirement, morbidity, length of hospital stay and recurrence rate (P < 0.001) |
Propensity score matching study | |||
Wei et al[67] (n = 325) | Impact of surgical modalities on long term survival outcomes | Similar | Similar: OS (HR 1.160; 95%CI: 0.662-2.033); DSS (HR 1.208; 95%CI: 0.686-2.128) |
Uppal et al[68] (n = 1084 of which 874 had resection) | Lymph node and stage; Survival; Adjuvant systemic therapy rate | Fewer and negative for disease; Better. 21.5% | Higher T3/4 stage, extra nodal involvement and performed more at academic center. Poorer, higher mortality, uninsured status. 31.3% |
- Citation: Lim KT. Current surgical management of duodenal gastrointestinal stromal tumors. World J Gastrointest Surg 2021; 13(10): 1166-1179
- URL: https://www.wjgnet.com/1948-9366/full/v13/i10/1166.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v13.i10.1166