Individualized treatment for gastric cancer with rib metastasis: A case report

Figure 4 Postoperative specimens and pathologies. A: Left 3rd rib metastasis; B: Pathology of metastasis, with complete regression and no metastatic tumor left (tumor regression grade classification: 0, × 100); C: Gastric cancer; D: Pathology of ulcerative gastric moderately differentiated adenocarcinoma that infiltrated into the submucosa and adjacent to the superficial muscle layer locally, low-grade intraepithelial neoplasia of some glands in the surrounding mucosa, and tumor stroma infiltrated with a small amount of inflammatory cells, with 1/36 lymph node metastasis (partial response, tumor regression grade classification: 2, × 100). Immunohistochemistry revealed CD34(+), blood vessels(+), CDX2(+), CgA(-), CK20(-), CK7(+), CKpan(+), CyclinD1(+), EGFR(+), Ki-67 (+75%), P53(+), Survivin(+), Syn(-), CerbB-2(2+), MLH1(+), MSH2(+), MSH6(+), and PMS2(+).