Partial pancreatic tail preserving subtotal pancreatectomy for pancreatic cancer: Improving glycemic control and quality of life without compromising oncological outcomes

Table 3 Perioperative and pathological outcomes

Parameter	PPTP-SP (n = 18)	TP (n = 38)	P value
Perioperative outcomes
Operative time (h), median (IQR)	6.7 (6.6-8.2)	7.3 (6.8-8.6)	0.076
Estimated blood loss (mL), median (IQR)	550 (400-800)	600 (500-1200)	0.386
Red cells transfusion (mL), median (IQR)	200 (200-600)	400 (200-1000)	0.249
Resection of PV/SMV, n (%)	11 (61.1)	21 (55.3)	0.680
Overall morbidity, n (%)	7 (38.9)	13 (34.2)	0.733
Major complications, n (%)	1 (5.6)	3 (7.9)	0.751
Delayed gastric emptying, n (%)	2 (11.1)	4 (10.5)	0.947
Pulmonary disease, n (%)	3 (16.7)	4 (10.5)	0.516
Chyle leakage, n (%)	1 (5.6)	3 (7.9)	0.751
Postpancreatectomy hemorrhage, n (%)	1 (5.6)	2 (5.3)	0.964
Abdominal collection, n (%)	1 (5.6)	1 (2.6)	0.582
Arrhythmia, n (%)	2 (11.1)	3 (7.9)	0.693
Biliary leakage, n (%)	0 (0.0)	0 (0.0)	-
Biochemical leak, n (%)	2 (11.1)	0 (0.0)	0.099
Grade B or C pancreatic fistula, n (%)	0 (0.0)	0 (0.0)	-
Reoperation, n (%)	0 (0.0)	0 (0.0)	-
Morality, n (%)	0 (0.0)	0 (0.0)	-
Readmission, n (%)	1 (5.6)	3 (7.9)	0.751
Postoperative staying (d), median (IQR)	9.5 (7-16)	11.5 (9-17.5)	0.286
Pathological outcomes
Histology, n (%)			0.153
PDAC without IPMN	18 (100.0)	34 (89.5)
PDAC concomitant with IPMN	0 (0.0)	4 (10.5)
Differentiation, n (%)			0.829
High	1 (5.6) 1 (5.6)	3 (7.9)
Moderate	11 (61.1)	20 (52.6)
Poor	6 (33.3)	15 (39.5)
Harvested lymph nodes (n), median (IQR)	12.5 (9-16)	14.5 (10-20)	0.521
Lymph node metastasis, n (%)	9 (50.0)	25 (65.8)	0.259
Paraaortic lymph node metastasis (#16), n (%)	1 (5.6)	7 (18.4)	0.199
Resection Margin, n (%)			0.487
R0	18 (100.0)	37 (97.4)
R1	0 (0.0)	1 (2.6)
Vascular invasion (SMV/PV), n (%)	9 (50.0)	17 (44.7)	0.712
Perineural invasion, n (%)	13 (72.2)	20 (52.6)	0.164
Colonic invasion, n (%)	0 (0.0)	1 (2.6)	0.487
Tumor size (cm), median (IQR)	4.3 (3.0-5.1)	4.4 (3.4-6.6)	0.408
T stage			0.445
T1	0 (0.0)	2 (5.3)
T2	8 (44.4)	13 (34.2)
T3	10 (55.6)	22 (57.9)
T4	0 (0.0)	1 (2.6)
N stage			0.502
N0	9 (50.0)	13 (34.2)
N1	7 (38.9)	18 (47.4)
N2	2 (11.1)	7 (18.4)
AJCC 8th stage			0.657
IA-IB	4 (22.2)	7 (18.4)
IIA-IIB	12 (66.7)	23 (60.5)
III	2 (11.1)	8 (21.1)
IV	0 (0.0)	0 (0.0)

PPTP-SP: Partial pancreatic tail preserving-subtotal pancreatectomy; TP: Total pancreatectomy; PV/SMV: Portal vein and/or superior mesenteric vein; PDAC: Pancreatic ductal adenocarcinoma; IPMN: Intraductal papillary mucinous neoplasm; AJCC: American Joint Committee on Cancer; IQR: Interquartile range.