Patients with Crohn’s disease have longer post-operative in-hospital stay than patients with colon cancer but no difference in complications’ rate

Table 1 Patients’ demographics, pre- and peri-operative patient characterization n (%)

Variables	CC n = 2515	CD n = 375	P value
Age (yr)1	71 (15)	37 (23)	< 0.01
Haemoglobin (g/dL)1	11.9 (3)	12.8 (2)	< 0.01
Gender Male Female	1310 (52.1) 1205 (48.9)	161 (42.9) 214 (57.1)	0.01
History of diabetes	463 (18.4)	7 (1.9)	< 0.01
History of IHD	548 (21.8)	10 (2.7)	< 0.01
BMI ≤ 18.5 18.6-25 25.1-30 > 30 Missing	57 (2.5) 926 (39.9) 867 (37.4) 468 (20.2) 197 (7.8)	43 (12.4) 209 (60.4) 72 (20.8) 22 (6.4) 29 (7.7)	< 0.01
ASA grade I II III IV V	250 (9.9) 1261 (50.1) 903 (35.9) 98 (3.9) 3 (0.01)	88 (23.5) 239 (63.7) 45 (12.0) 3 (0.8) 0 (0)	< 0.01
Abnormal s. creatinine	294 (11.6)	13 (3.5)	< 0.01
Smoking status Non-smoker Current smoker Ex-smoker Missing	1587 (63.1) 268 (10.7) 486 (19.3) 174 (6.9)	219 (58.4.1) 81 (23.1) 52 (14.8) 23 (6.1)	< 0.01
Previous surgery in the area	607 (24.1)	122 (32.5)	< 0.01
Urgency of surgery Elective/expedited Emergency	2216 (88.1) 299 (11.9)	321 (85.6) 54 (14.4)	0.130
Surgeon in charge Colorectal surgeon General surgeon	1798 (71.5) 717 (28.5)	313 (83.5) 62 (16.5)	< 0.01
Operative approach Laparoscopy Converted to open Open	1221 (48.5) 219 (8.7) 1075 (42.7)	177 (47.2) 42 (11.2) 156 (41.6)	0.317
Type of resection Ileocecal resection Right hemicolectomy	125 (5.0) 2390 (95.0)	266 (70.9) 109 (29.1)	< 0.01
De-functioning stoma	78 (3.1)	46 (12.3)	< 0.01
Skin closure technique Suture closure Stapled Others	842 (33.5) 1450 (57.7) 223 (8.9)	196 (52.2) 145 (38.7) 34 (9.1)	< 0.01
Unplanned Intra-operative events2	230 (9.15)	56 (14.9)	< 0.01
Duration of operation (minutes)1	130 (65)	128 (59)	0.831

Patients with Crohn’s disease were younger, with lower American Society of Anesthesiology score grade, less comorbidity, operated on by experienced surgeons and underwent less extensive surgery. Pre- and peri-operative patient characterization (n/%). Missing data were observed in the following variables: “Age”, “BMI”, “Smoking status”, “Haemoglobin” and “Duration of operation”.

¹Median (IQR);

²Some patients may have more than one unplanned intra-operative event. IHD: Ischemic heart diseases; CRP: C-reactive protein; BMI: Body mass index; CD: Crohn’s disease; CC: Colon cancer; UIAEs: Unplanned intraoperative adverse events; ASA: American Society of Anesthesiology score.