Acquired segmental colonic hypoganglionosis in an adult Caucasian male: A case report

Figure 6 Calretinin staining. A: Low-power (magnification × 40) calretinin staining of nerve in diseased colon showing one isolated mature ganglion cell (dark brown cell, arrow) and markedly reduced density (0.2/mm²); B: Low-power (magnification × 40) calretinin staining of normal colon showing normal density (5/mm²) of mature ganglion cells (numerous dark brown cells); C: High-power (magnification × 400) calretinin stain in diseased colon showing failure of immature ganglion cells to stain (pale brown cells); D: High-power (magnification × 400) calretinin staining of normal colon showing abundance of mature ganglion cells (dark brown cells).