Prevalence and risk factors of wound complications after transtibial amputation in patients with diabetic foot

Table 1 Demographics, n (%)

		Group 1 (n = 41)	Group 2 (n = 31)	P value
Age (years), mean ± SD				0.66
		66.0 (9.9)	61.4 (10.9)
	Median (Q1 to Q3)	65.0 (59.0 to 74.0)	61 (56.0 to 66.5)
Sex				0.93
	Female	13 (31.7)	11 (35.5)
	Male	28 (68.3)	20 (64.5)
BMI, mean ± SD				0.64
		22.4 (3.8)	22.8 (3.8)
	Median (Q1 to Q3)	22.5 (19.5 to 24.4)	22.2 (19.5 to 25.7)
Location				0.92
	Right	16 (39.0)	14 (45.2)
	Left	23 (56.1)	16 (51.6)
	Both	2 (4.9)	1 (3.2)
Dialysis				0.86
	No	31 (75.6)	22 (71.0)
	Yes	10 (24.4)	9 (29.0)
Kidney transplant history				0.02
	No	40 (97.6)	21 (67.7)
	Yes	1 (2.4)	10 (32.3)
Smoking				0.71
	No	29 (70.7)	24 (77.4)
	Yes	12 (29.3)	7 (22.6)
Amputation history				0.84
	No	22 (53.7)	15 (48.4)
	Yes	19 (46.3)	16 (51.6)
HTN				0.06
	No	17 (41.5)	4 (12.9)
	Yes	24 (58.5)	27 (87.1)
Endovascular intervention history				0.38
	No	29 (70.7)	18 (58.1)
	Yes	12 (29.3)	13 (41.9)
HbA1		7.54	9.32	0.01
HbA1c ≥ 7.2				0.01
	No	18 (43.9)	4 (12.9)
	Yes	23 (56.1)	27 (87.1)

BMI: Body mass index; HTN: Hypertension; HbA1c: Hemoglobin A1c.

Table 2 Risk factors

		Univariable		Multivariable_all
		OR (95%CI)	P value	OR (95%CI)	P value
Age (years)		0.96 (0.91-1.00)	0.066	1.01 (0.93-1.09)	0.866
Sex
	Female	-		-
	Male	0.84 (0.31-2.29)	0.737	0.53 (0.08-2.92)	0.476
BMI		1.03 (0.91-1.17)	0.630	1.10 (0.87-1.45)	0.439
Location
	Right	-		-
	Left	0.80 (0.30-2.08)	0.640	0.62 (0.14-2.65)	0.525
	Both	0.57 (0.02-6.60)	0.662	0.11 (0.00-3.08)	0.239
Kidney transplant history
	No	-		-
	Yes	19.05 (3.32-361.72)	0.006a	26.22 (2.36-811.46)	0.020
Smoking
	No	-		-
	Yes	0.70 (0.23-2.04)	0.525	0.26 (0.04-1.52)	0.150
ICU
	No	-		-
	Yes	0.64 (0.23-1.71)	0.379	0.20 (0.03-1.09)	0.085
HTN
	No	-		-
	Yes	4.78 (1.52-18.42)	0.012	6.19 (1.20-44.22)	0.054
Endovascular intervention history
	No	-		-
	Yes	1.75 (0.66-4.72)	0.266	2.86 (0.63-16.12)	0.193
HbA1c ≥ 7.2
	No	-		-
	Yes	5.28 (1.69-20.33)	0.007a	31.28 (5.04-355.9)	0.001

^aP < 0.05.

BMI: Body mass index; ICU: Intensive care unit; HTN: Hypertension; HbA1c: Hemoglobin A1c; OR: Odds ratio; CI: Confidence interval.