Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis

Table 1 Changes in paired A1C and random blood glucose surrounding medication-initiation events

Medication	n	Difference (mg/dL or % glycosylation)	Confidence interval		P value
Random blood glucose
Etanercept	311	-0.06	-4.91	4.79	0.98
Adalimumab	302	1.03	-3.41	5.46	0.65
Certolizumab	5	-5.20	-26.60	16.19	0.54
Golimumab	13	-17.61	-37.54	2.31	0.08
Infliximab	147	-1.90	-9.45	5.65	0.62
Methotrexate	831	2.08	-7.48	4.90	0.15
Leflunomide	290	-0.48	-6.84	5.88	0.88
Hydroxychloroquine	653	-3.68	-7.15	0.20	0.04
Sulfasalazine	335	-0.38	-4.92	4.17	0.87
Prednisone	665	5.85	2.20	9.51	< 0.01
Hemoglobin A1C
Etanercept	35	-0.17	-0.50	0.17	0.33
Adalimumab	43	0.04	-0.34	0.42	0.83
Certolizumab	1	0.20	n/a	n/a	n/a
Golimumab	4	-0.65	-3.47	2.17	0.52
Infliximab	20	-0.36	-0.95	0.23	0.22
Methotrexate	107	-0.11	-0.35	0.14	0.40
Leflunomide	51	-0.02	-0.40	0.35	0.91
Hydroxychloroquine	98	-0.15	-0.40	0.11	0.25
Sulfasalazine	49	-0.70	-1.08	0.31	< 0.01
Prednisone	68	-0.01	-0.25	0.24	0.96

n/a: Insufficient numbers to calculate.