Pathological changes in the cellular structures of retina and choroidea in the early stages of alloxan-induced diabetes

Figure 9 Posterior wall of the eye of an animal with diabetes at 60 d. A: Light microscopy of the retina; *: interstitial edema; v: full blood vessels; B: Electron microscopy of the outer layers of the retina; *: destruction of rods and cones; C: Light microscopy of the choroid of the eye; *: interstitial edema; v: full blood vessels with swollen endothelial cells; RPE: destructive changes in retinal pigment epithelial cells; MCh: destruction of pigment cells of the choroid; D: Electron microscopy of the retinal pigment epithelium and choroid; MB: uneven Bruch’s membrane with invagination sites; MCh: choroidal melanocyte with reduced amount of pigment granules; P: destructive changes in the outgrowths of retinal pigment epithelial cells; Light microscopy: staining with hematoxylin and eosin, magnification × 400, bar 50 μm; Electron microscopy: bar 10 μm.