Effects of glucose-lowering agents on cardiorespiratory fitness

doi:10.4239/wjd.v9.i12.230

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Dec 15, 2018; 9(12): 230-238
Published online Dec 15, 2018. doi: 10.4239/wjd.v9.i12.230

Table 5 Effect of glucose-lowering agents on cardiorespiratory fitness

Glucose-lowering agents	Cardiorespiratory fitness
Metformin	→ or ↓
Thiazolidinediones	↑
DPP-4 inhibitors	Unknown
DPP-4 inhibitors	(↑ in mice with heart failure)
GLP-1 receptor agonists	↑ in patients with heart failure
GLP-1 receptor agonists	→ in patients with type 2 diabetes
SGLT2 inhibitors	↑ in patients treated with loop diuretics

DPP-4: Dipeptidyl peptidase-4; GLP-1: Glucagon-like peptide-l; SGLT2: Sodium–glucose cotransporter 2.

Citation: Hamasaki H. Effects of glucose-lowering agents on cardiorespiratory fitness. World J Diabetes 2018; 9(12): 230-238
URL: https://www.wjgnet.com/1948-9358/full/v9/i12/230.htm
DOI: https://dx.doi.org/10.4239/wjd.v9.i12.230