Short-term effects of obestatin on hexose uptake and triacylglycerol breakdown in human subcutaneous adipocytes

Table 2 Influence of obestatin on antilipolytic and glucose transport activities of human subcutaneous adipocytes

	n	Treatment	Control	Obestatin 1 nmol/L	Obestatin 10 nmol/L	Obestatin 100 nmol/L	UK14304 1 μmol/L
Lipolysis, µmol glycerol/ 100 mg lipid/90 min	3	Isoprenaline	0.64 ± 0.10	0.61 ± 0.09	0.62 ± 0.10	0.62 ± 0.10	0.29 ± 0.04a
Glucose transport, nmol 2-DG/100 mg lipids/10 min	10	Insulin	0.46 ± 0.14	0.45 ± 0.09	0.45 ± 0.09	0.43 ± 0.09	ND

Fat cells were incubated with a submaximal dose of the reference activator of lipolysis (isoprenaline 100 nmol/L), or glucose transport (insulin 5 nmol/L) alone (control) or with the indicated agents. Mean ± SEM. Different from corresponding control at:

^aP < 0.05. ND: Not determined.