Age-dependent changes in the association between sleep duration and impaired glucose metabolism

Table 3 Odds ratios (95%CIs) of sleep duration for prediabetes and diabetes in younger subjects n (%)

Sleep durations	≤ 5 h	6 h	7 h	≥ 8 h	P value
Prediabetes
Cases	418 (10.2)	1463 (9.0)	743 (7.9)	229 (7.2)
Model 1	1.32 (1.16-1.49)d	1.15 (1.05-1.26)b	1 (reference)	0.90 (0.77-1.05)	0.88 (0.84-0.92)d
Model 2	1.32 (1.16-1.50)d	1.18 (1.07-1.29)b	1 (reference)	0.89 (0.76-1.04)	0.87 (0.83-0.91)d
Model 3	1.20 (1.05-1.37)b	1.12 (1.02-1.24)a	1 (reference)	0.84 (0.72-0.99)a	0.90 (0.86-0.95)d
Diabetes
Cases	58 (1.4)	150 (0.9)	77 (0.8)	27 (0.9)
Model 1	1.73 (1.23-2.44)b	1.12 (0.85-1.42)	1 (reference)	1.04 (0.67-1.61)	0.83 (0.72-0.96)a
Model 2	1.72 (1.22-2.43)b	1.16 (0.88-1.52)	1 (reference)	1.01 (0.65-1.58)	0.83 (0.72-0.95)b
Model 3	1.35 (0.93-1.97)	1.02 (0.76-1.37)	1 (reference)	0.92 (0.58-1.46)	0.90 (0.78-1.04)

Model 1: Unadjusted; Model 2: Adjusted for age and sex; Model 3: Model 2 plus adjustment for current smoking (vs non-smoking), daily alcohol consumption (vs infrequent/no alcohol consumption), regular exercise (vs no regular exercise), pharmacotherapy (hypertension, diabetes, and dyslipidemia), BMI, WBC count, systolic blood pressure, triglycerides, HDL-cholesterol, duration of work (as continuous variables), and past history of CVD (vs no history). Triglyceride concentrations were log transformed before analysis. Regular exercise was defined as ≥ 30 min exercise per session at least twice a week.

^aP < 0.05,

^bP < 0.01,

^dP < 0.001. BMI: Body mass index; HDL: High-density lipoprotein; CVD: Cardiovascular disease; WBC: White blood cell.