Saponins as adipokines modulator: A possible therapeutic intervention for type 2 diabetes

doi:10.4239/wjd.v8.i7.337

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World Journal of Diabetes

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1948-9358

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World J Diabetes. Jul 15, 2017; 8(7): 337-345
Published online Jul 15, 2017. doi: 10.4239/wjd.v8.i7.337

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Figure 4 Modulation of adipokines (peptides) by saponin. Saponin increases the expression of leptin, adiponectin, adipsin, visfatin but reduces the expression of apelin. PI3K: Phosphatidylinositol 3-kinase; AKT: Protein kinase B; MAPK: Mitogen activated protein kinase; AMPK: 5’AMP-activated protein kinase; STAT3: Signal tranducer and activator of transcription 3; JAK2: Janus kinase 2.

Citation: Elekofehinti OO, Ejelonu OC, Kamdem JP, Akinlosotu OB, Adanlawo IG. Saponins as adipokines modulator: A possible therapeutic intervention for type 2 diabetes. World J Diabetes 2017; 8(7): 337-345
URL: https://www.wjgnet.com/1948-9358/full/v8/i7/337.htm
DOI: https://dx.doi.org/10.4239/wjd.v8.i7.337