Saponins as adipokines modulator: A possible therapeutic intervention for type 2 diabetes

doi:10.4239/wjd.v8.i7.337

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jul 15, 2017; 8(7): 337-345
Published online Jul 15, 2017. doi: 10.4239/wjd.v8.i7.337

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Figure 3 Adipsin and insulin secretion in beta cell. Adipsin potentiates insulin secretion through cleavage of CFB to form C3 that is hydrolyzed to form C3a. C3a activates C3AR1, which acts on B-cells of the pancreas to secret insulin. CFB: Complement factor B.

Citation: Elekofehinti OO, Ejelonu OC, Kamdem JP, Akinlosotu OB, Adanlawo IG. Saponins as adipokines modulator: A possible therapeutic intervention for type 2 diabetes. World J Diabetes 2017; 8(7): 337-345
URL: https://www.wjgnet.com/1948-9358/full/v8/i7/337.htm
DOI: https://dx.doi.org/10.4239/wjd.v8.i7.337