Interleukin-18 polymorphism as an inflammatory index in metabolic syndrome: A preliminary study

Table 3 Genotype frequency among study subjects

Genotype distribution
	CC	AC	AA	P value
Normal weight	27	23	10	< 0.001
Overweight	11	25	24
Obese	12	24	24
Allele frequency
	A allele	C allele	OR (95%CI)	P value
Normal weight	42 (35.0)	78 (65.0)	-	-
Overweight	47 (39.17)	73 (60.83)	2.81 (1.66-4.68)1	< 0.001
Obese	48 (40.00)	72 (60.00)	2.91 (1.72-4.94)2

In all divisions the HWE was > 0.05.

¹Normal weight vs overweight and

²normal weight vs obese calculated by Pearson’s χ² test. Allele frequencies are given as absolute values with percentage given in parentheses.