Interleukin-18 polymorphism as an inflammatory index in metabolic syndrome: A preliminary study

Table 2 Correlation of interleukin-18 with metabolic syndrome phenotypes

Variable	Unadjusted r	Adjusted r (age, BMI and body fat %)
Age (yr)	0.302	--
BMI (kg/m2)	0.751	--
Body fat (%)	0.518	--
Waist circumference (cm)	0.333	0.413
Hip circumference (cm)	0.695	-0.110NS
Fasting blood glucose (mg/dL)	0.559	0.376
Insulin (uIU/mL)	0.655	0.205NS
HOMA-IR	0.699	0.344
QUICKI	-0.600	-0.496
Cholesterol (mg/dL)	0.514	0.265
LDL(mg/dL)	0.464	0.245
TNFα	0.577	0.491

Pearson Correlation was applied. All associations remained significant after adjustment except insulin (^NSnon-significant), statistically significant P value < 0.01. HOMA-IR: Homeostasis model of insulin resistance; QUICKI: Quantitative insulin sensitivity check index; LDL: Low density lipoprotein; TNF: Tumor necrosis factor.