Impact of creatinine methodology on glomerular filtration rate estimation in diabetes

Table 2 Clinical characteristics of the study subjects across the Kidney Disease Improving Global Guidelines-2012 categories of albuminuria

	Category of Albuminuria
	A1	A2	A3
N (M/F)	372 (212/198)	166 (87/79)	72 (38/34)
Age (yr)	63 (19-88)	68 (18-88)	60a,b (29-85)
Glucose (mmol/L)	9.0 (8.8-9.3)	9.4 (8.9-10.0)	7.4a,b (5.7-8.9)
HbA1c (%)	7.4 (7.3-7.6)	7.5 (7.3-7.7)	7.8 (7.4-8.5)
HbA1c (mmol/mol)	59 (57-61)	59 (57-61)	62 (58-71)
e-SCr (μmol/L)	69b,d (66-72)	75a,d (72-77)	100a,b (88-137)
cJ-SCr (μmol/mol)	70b,d (67-72)	77a,d (72-81)	108a,b (87-140)
e-SCr-eGFR (mL/min per 1.73 m2)	91b,d (88-93)	85a,d (80-88)	60a,b (39-77)
cJ-SCr-eGFR (mL/min per 1.73 m2)	90b,d (87-92)	83a,d (76-86)	55a,b (39-73)

Age is expressed as median (range) and other variables as median (95%CI of median).

^aP < 0.001 vs A1;

^bP < 0.001 vs A2;

^dP < 0.001 vs A3. HbA_1c: Glycosylated hemoglobin; SCr: Serum creatinine; eGFR: Estimated glomerular filtration rate; e: Enzymatic; cJ: Compensated Jaffé; M: Male; F: Female.