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Copyright ©The Author(s) 2017.
World J Diabetes. Mar 15, 2017; 8(3): 97-103
Published online Mar 15, 2017. doi: 10.4239/wjd.v8.i3.97
Figure 2
Figure 2 Casitas b-lineage lymphoma-b suppresses macrophage migration. Monocyte chemoattractant protein (MCP)-1 causes macrophages to infiltrate adipose tissue via C-C chemokine receptor 2 (CCR2). Phosphorylation (P) of Vav1 mediates macrophage migration, and Cbl-b negatively regulates macrophage migration by suppressing Vav1 phosphorylation.