Copyright
©The Author(s) 2016.
World J Diabetes. May 10, 2016; 7(9): 189-197
Published online May 10, 2016. doi: 10.4239/wjd.v7.i9.189
Published online May 10, 2016. doi: 10.4239/wjd.v7.i9.189
Figure 3 Three conformations of human amylin.
Monomers of amylin with physiological functions mainly contribute to glucose and lipid homeostasis and tend to misfold into the cytotoxic oligomers. A self-driven process is accumulating the misfolded oligomers into insoluble nontoxic amylin fibrils with a β-sheet structure.
- Citation: Zhang XX, Pan YH, Huang YM, Zhao HL. Neuroendocrine hormone amylin in diabetes. World J Diabetes 2016; 7(9): 189-197
- URL: https://www.wjgnet.com/1948-9358/full/v7/i9/189.htm
- DOI: https://dx.doi.org/10.4239/wjd.v7.i9.189