Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants

Table 6 Calculated percentage change in blood glucose after treatment with the extracts in streptozotocin-induced diabetic rats

Group	Initial blood glucose on day 0 (mg/dL)	Percentage change after treatment (%)
		Day 7	Day 14	Day 21
CME	344.6 ± 10.3	18.0 ± 2.66e	43.3 ± 3.62e	69.1 ± 1.03c
SEE	396.8 ± 15.7	13.7 ± 0.29d	33.3 ± 1.60c,d	69.5 ± 0.71c
MAE	373.3 ± 13.6	11.2 ± 0.18c,d	36.5 ± 0.08d	72.6 ± 1.03d
PC	389.4 ± 11.9	7.8 ± 0.42c	31.6 ± 1.30c	75.0 ± 0.73d
NC	365.5 ± 9.8	-8.1 ± 1.57a	-14.8 ± 0.29a	-22.7 ± 1.47a
HC	84.8 ± 4.7	1.4 ± 3.96b	0.1 ± 2.12b	0.7 ± 2.88b

Same superscript down the column signifies no significant difference at P > 0.05. Percentage change in blood glucose = [(blood glucose before treatment - blood glucose after treatment)/blood glucose before treatment] × 100. CME: Cold maceration extract; SEE: Soxhlet extraction extract; MAE: Microwave-Assisted Extraction extract; PC: Positive control; NC: Negative control; HC: Healthy control.