Gestational diabetes mellitus: Screening with fasting plasma glucose

Table 3 Studies using fasting glucose to avoid oral glucose tolerance test

OGTTs circumvented (n, %)	Thresholds (lower and higher) mmol/L	OGTT (g)	Diagnostic criteria	Comments	Ref.
50.9	4.4 and 5.3	100	ADA (C and C)	Biased sampling: Preselected by clinical/GCT	Agarwal et al[32]
30.1	4.7 and --	75	WHO-1999	Only lower threshold used to rule out GDM	Agarwal et al[39]
63.8	4.9 and 7.0	75	ADA (C and C)	FPG screening dependent on GDM criteria	Agarwal et al[40]
68.5	4.9 and 7.0	75	ADA (C and C)	Glucometer used for FPG	Agarwal et al[60]
50.1	4.7 and 7.0	75	ADA (C and C)	Fasting capillary glucose used	Agarwal et al[57]
50.6	4.4 and 5.1	75	IADPSG	Pooled data from 4 studies	Agarwal et al[61]
50.3	4.4 and 5.1	75	IADPSG	Data from China corroborating UAE data	Zhu et al[62]
61.0	4.4 and 5.1	75	IADPSG	Data from Brazil corroborating UAE data	Trujillo et al[63]
57.0	4.4 and 5.1	75	IADPSG	Thresholds applied to HAPO Study	Agarwal et al[77]

OGTT: Oral glucose tolerance test; ADA: American Diabetes Association; WHO: World Health Organization; IADPSG: International Association of Diabetes and Pregnancy Study Groups; C and C: Carpenter-Coustan; GCT: Glucose challenge test; GDM: Gestational diabetes mellitus; FPG: Fasting plasma glucose; UAE: United Arab Emirates; HAPO: Hyperglycemia and Adverse Pregnancy Outcome.