Gestational diabetes mellitus: Screening with fasting plasma glucose

Table 2 Studies about fasting plasma glucose as a screening test

n	Cut-off mmol/L	Se (%)	Sp (%)	GDM (%)	AUC	Glucose load (g)	OG criteria1	Ref.
Without selection bias
5010	4.5	81.5	54	7.6	--	75	WHO-1985	Reichelt et al[37]
558	4.8	81	76	10.2	0.897	100	ADA	Perucchini et al[27]
942	4.1	> 70		13	0.766	75	WHO-1985	Tam et al[38]
1685	4.7	78.1	32.2	19.8	0.639	75	WHO-1999	Agarwal et al[39]
500	4.7	88	95	7.2	--	100	C and C-1982	Poomalar et al[41]
In early pregnancy
4507	4.6	80	43	6.7	0.7	75	Sacks	Sacks et al[46]
708	4.7	79.9	27.5	25.9	0.579	75	WHO-1999	Agarwal et al[47]
4876	4.4	79	46.9	2.8	0.72	100	C and C 100-g OGTT	Riskin-Mashiah et al[49]
17186	4.3	84	29	12.4	--	75	IADPSG	Zhu et al[51]
486	--	47.2	77.4	10.9	0.623	--	FPG > 5.1 mmol/L	Yeral et al[53]

¹Fasting plasma glucose (FPG) threshold with Specificity (Sp) corresponding to Sensitivity (Se) about 80%. AUC: Area under receiver operating characteristic curve; C and C: Carpenter-Coustan; ADA: American Diabetes Association; WHO: World Health Organization; IADPSG: International Association of Diabetes and Pregnancy Study Groups; OGTT: Oral glucose tolerance test; GDM: Gestational diabetes mellitus.