Functions of M&uuml;ller cell-derived vascular endothelial growth factor in diabetic retinopathy

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Jun 10, 2015 (publication date) through Nov 21, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jun 10, 2015; 6(5): 726-733
Published online Jun 10, 2015. doi: 10.4239/wjd.v6.i5.726

Table 2 Pathological changes in diabetic or hypoxic Müller cell-specific KO mice

Model	Pathological changes	Alteration
STZ-induced diabetes	Leukocytosis	Decrease (75%)
STZ-induced diabetes	Vascular leakage	Decrease (60%)
STZ-induced diabetes	Acellular capillaries	Decrease (45%)
STZ-induced diabetes	Vascular leakage	Decrease (60.0%)
Oxygen-induced retinopathy	Pre-retinal neovascularization	Decrease (34%)
Oxygen-induced retinopathy	Neovascularization area	Decrease (40%)
Oxygen-induced retinopathy	Vaso-obliteration area	Decrease (30%)

STZ: Streptozotocin.

Citation: Wang JJ, Zhu M, Le YZ. Functions of Müller cell-derived vascular endothelial growth factor in diabetic retinopathy. World J Diabetes 2015; 6(5): 726-733
URL: https://www.wjgnet.com/1948-9358/full/v6/i5/726.htm
DOI: https://dx.doi.org/10.4239/wjd.v6.i5.726