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Copyright ©The Author(s) 2015.
World J Diabetes. Jun 10, 2015; 6(5): 726-733
Published online Jun 10, 2015. doi: 10.4239/wjd.v6.i5.726
Table 1 Alteration in protein expression/modification in diabetic or hypoxic Müller cell-specific KO mice
Model/timeProteins/modificationAlteration
STZ-induced diabetes/6 moAlbuminDecrease (59%)
STZ-induced diabetes/2 moICAM1Decrease (62%)
STZ-induced diabetes/2 moNitrotyrosineDecrease (19%)
STZ-induced diabetes/6 moOccludinIncrease (60%)
STZ-induced diabetes/2 mopNF-κB p65Decrease (48%)
STZ-induced diabetes/2 moTNF1αDecrease (53%)
STZ-induced diabetes/6 moVEGFDecrease (51%)
STZ-induced diabetes/6 moZO1Increase (130%)
Oxygen-induced retinopathyAlbuminDecrease (56%)
Oxygen-induced retinopathyVEGFDecrease (45%)
Oxygen-induced retinopathyOccludinIncrease (35%)