Advanced glycation end-product expression is upregulated in the gastrointestinal tract of type 2 diabetic rats

Figure 3 Example of advanced glycation end products immune-staining in esophagus (A, normal; B, diabetic); C: Shows the statistic result of immune-staining intensity in esophagus muscle and mucosa. Values are mean ± SD, n = 8 for each group (compared with normal group: ^bP < 0.01). The immune-positive area of AGE showed yellow-brown color. Eso mus: Esophageal muscle; Eso muc: Esophageal mucosa; GK: Inherited type 2 diabetic Goto-Kakizak rats; AGE: Advanced glycation end product. Blue arrow: mucosa; Red arrows: Submucosa; Black arrows: Muscle.