Nociception at the diabetic foot, an uncharted territory

Table 3 Percentages of subjects with active diabetic podopathy (ulcer, arthropathy) according to loss of nociception

Foot morbidity	Degree of loss of nociception			Ref.
	None	Mild/moderate	Severe
	(CPPPT1 approximately 100 mN)	(CPPPT1 < 512 mN)	(CPPPT1 > 512 mN)	[59]
Past/present painless ulcer	0%	0%	100%	[28,59,77,86-101]
Foot ulcer, incidence per year	Approximately 0%-1%	Approximately 6%-15%	Approximately 20%-100%2	[28,77,86-101]
Charcot-foot, prevalence	Approximately 0%	Approximately 0.05%	Approximately 2%	[102]

¹Cutaneous pressure pain perception threshold, pinprick stimulator, upper limit of measurement 512 mN, measured at a plantar digital skinfold;

²Depending on compliance with prophylactic podiatry and/or special footwear. CPPPT: Cutaneous pressure pain perception threshold.