Association of gene variants with susceptibility to type 2 diabetes among Omanis

Table 3 Fixation index, heterozygosity, Fst and % variation among Omani type 2 diabetes mellitus patients and control participants

Gene	Gene variants	T2D patients		Controls		Fst	% variation among T2D and controls	1P value
		F	He	F	He
KCNJ11	rs5219	0.190	0.352	0.091	0.314	0.012	2.07	0.000
TCF7L2	rs7903146	0.017	0.486	0.000	0.476	0.009	1.62	0.000
CDKAL1	rs10946398	0.084	0.424	0.056	0.405	0.003	0.48	0.020
CDKN2A/B	rs10811661	0.000	0.275	0.003	0.320	0.002	0.37	0.042
FTO	rs9939609	0.000	0.502	0.000	0.497	0.002	0.31	0.050
FTO	rs8050136	0.006	0.493	0.000	0.503	0.001	0.12	0.147
IGF2BP2	rs4402960	0.066	0.448	0.000	0.476	0.002	0.23	0.089
SLC30A8	rs13266634	0.061	0.230	0.188	0.201	0.000	0.00	1.000
CAPN10	rs3792267	0.057	0.300	0.000	0.335	0.000	0.00	0.517
HHEX	rs1111875	0.055	0.398	0.052	0.382	0.001	0.00	0.341

This provides a measure of genetic differentiation among population; ¹P value: Level of significance; F: Fixation index; He: Heterozygosity; Fst: The inbreeding coefficient within subpopulation, relative to total; T2D: Type 2 diabetes mellitus.