Diabetic cardiac autonomic neuropathy: Do we have any treatment perspectives?

Table 5 Changes of day arterial stiffness parameters after 3 mo omega-3 polyunsaturated fatty acid therapy

	Patients with T2DM and CAN (n = 39)
	Groups	Baseline	After treatment	% change from baseline
AIxao (%)	Control group	30.4 ± 1.97	28.4 ± 1.68	-4.3% ± 4.76%
	Treatment group	32.0 ± 1.32	26. 4 ± 1.12b	-16.2% ± 3.12%
AIxbr (%)	Control group	-10.6 ± 3.37	-12.0 ± 3.11	-19.3% ± 12.14%
	Treatment group	-9.8 ± 2.76	-14.3 ± 2.84	-42.8% ± 9.0%
PWV (m/s)	Control group	10.2 ± 0.4	9.6 ± 0.4	-6.0% ± 2.21%
	Treatment group	11.0 ± 0.35	9.7 ± 0.39a	-11.6% ± 2.09%

The results are given as absolute values and as % change from baseline, (Δ%, Mean ± SEM);

^aP < 0.05,

^bP < 0.01, - compared to baseline. T2DM: Type 2 diabetes mellitus; CAN: Cardiac autonomic neuropathy; AIxao: Aortha augmentation index; AIxbr: Brachial augmentation index; PWV: Pulse wave velocity.