Erythropoietin and diabetes mellitus

Figure 2 Targeting erythropoietin involves a balance that fosters clinical improvement over clinical disability. EPO can play a significant role in reducing disability and fostering clinical benefit during diabetes mellitus. Through its signal transduction pathways, EPO may improve organ and tissue function, reduce fatigue, improve vascular perfusion, maintain glucose homeostasis, assist with wound and tissue repair, and promote cellular proliferation, differentiation, and survival. However, the detrimental effects of EPO that can include tumor cell growth, hypertension, increased blood viscosity, and unchecked angiogenesis must be considered and eliminated for successful therapeutic treatments against diabetes mellitus. EPO: Erythropoietin.