Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats

doi:10.4239/wjd.v6.i10.1168

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Aug 25, 2015; 6(10): 1168-1178
Published online Aug 25, 2015. doi: 10.4239/wjd.v6.i10.1168

Table 2 Body weight (g) of diabetic and control rats treated with statins

Condition	Day 0	Day 1	Day 7	Day 14	Day 28
CT none	179.74 ± 4.02	182.28 ± 4.15	242.78 ± 6.18	304.06 ± 13.26	391.34 ± 9.80
CT + AV	167.17 ± 4.38	172.97 ± 4.53	234.77 ± 5.27	287.67 ± 4.67	404.10 ± 12.46
CT + SV	181.89 ± 8.26	184.19 ± 8.12	248.40 ± 7.99	291.69 ± 6.93	394.14 ± 15.92
CT + PV	193.81 ± 8.25	198.85 ± 7.66	262.99 ± 9.03	301.19 ± 8.02	389.64 ± 11.48
Diabetic none	180.22 ± 5.99	172.53 ± 5.24	198.19 ± 7.41	211.94 ± 11.11^a	267.10 ± 27.98^a
Diabetic + AV	176.30 ± 3.10	159.86 ± 9.93	202.32 ± 5.13	235.45 ± 8.56^a	255.40 ± 17.09^a
Diabetic + SV	183.14 ± 4.68	178.24 ± 4.29	207.69 ± 6.81	230.13 ± 7.23^a	241.65 ± 12.73^a
Diabetic + PV	187.88 ± 5.62	182.58 ± 4.60	204.85 ± 7.18	243.69 ± 5.60^a	253.99 ± 11.82^a

^aP < 0.05 vs age-matched C. Values are means ± SEM. Rats were injected with STZ on day 0. Blood glucose for diabetic rats: n = average of 10 rats per group. STZ: Streptozotocin; AV: Atorvastatin; SV: Simvastatin; PV: Pravastatin; CT: Control.

Citation: Crespo MJ, Quidgley J. Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats. World J Diabetes 2015; 6(10): 1168-1178
URL: https://www.wjgnet.com/1948-9358/full/v6/i10/1168.htm
DOI: https://dx.doi.org/10.4239/wjd.v6.i10.1168