Dysglycemia after renal transplantation: Definition, pathogenesis, outcomes and implications for management

Table 1 Selection of studies that reported rates of new-onset diabetes after transplantation or other dysglycemic states

Ref.	Criteria	n	Rates
Cosio et al[3]	Use of medications, F BGL	490	13% at 1 yr
			33% dysglycemic
Hjelmesaeth et al[4]	Use of medications, F BGL, oGTT	201	20% at 3 mo
Vincenti et al[5]	oGTT	682	30% at 6 mo dysglycemic
Delgado et al[6]	oGTT, F BGL	374	6.7% at 4.1 yr
			25.1% dysglycemic
Ramesh Prasad et al[7]	F BGL or R BGL	151	20.5%
Luan et al[8]	oGTT	203	11.8% at 10 wk
			47.8% dysglycemic
Bayer et al[9]	Use of medications, F BGL, R BGL	640	31.4% at 1 yr
Bergrem et al[10]	Use of medications, F BGL, R BGL	301	13% at 10 wk
Valderhaug et al[11]	oGTT	1410	17% at 10 wk
			38% dysglycemic
Ciancio et al[12]	Use of medications	150	15%-22% at 4 yr
Israni et al[13]	Medications, F BGL	1840	13% at 5 yr
Wauters et al[14]	Use of medications, F BGL	1146	14.1% at 1 mo, 11.1% at 4 mo, 13.4% at 1 yr
			27%, 34.3% and 29.8% dysglycemic
Chan et al[15]	oGTT	292	24% at 6 mo
Vacher-Coponat et al[16]	Use of medications	289	16.8%-18.8% at 3 yr
Tillman et al[17]	oGTT	200	5% at 39 mo
			30.5% dysglycemic
Bonet et al[18]	F BGL, R BGL, oGTT	138	13% at 6 mo
Cole et al[19]	Use of medications, F BGL, oGTT	49	4% at 6 mo
Nagaraja et al[20]	Use of medications, F BGL	118	21% at 3 mo, 37% at 1 yr
First et al[21]	Use of medications, F BGL, HbA1c	634	17.8%-36.5% at 1 yr
Nagaraja et al[22]	oGTT	76	13% at 5 yr, 24% at 11 yr
			42% and 61% dysglycemic
Tokodai et al[23]	Use of medications, F BGL, R BGL	145	11.7% at 1 yr
Viecelli et al[24]	oGTT	83	17% at 3 mo, 15% at 15 mo
			31% and 21% dysglycemic
Weng et al[25]	Use of medications, F BGL, R BGL	166	29.5%
Schweer et al[26]	R BGL, HbA1c	526	16.7%
Prasad et al[27]	oGTT	439	20% at 3 mo
			33% dysglycemic
Silva et al[28]	HbA1c	638	21.3%-41.1% at 4 yr
Lv et al[29]	F BGL	428	20.3% at 5.7 yr

Definitions diabetes: F BGL ≥ 7.0 mmol/L (126 mg/dL) or ≥ 11.1 mmol/L (200 mg/dL) on oGTT or R BGL ≥ 11.1 mmol/L (200 mg/dL) plus symptoms. Other dysglycemic states. IFG: ADA criteria 5.6-6.9 mmol/L (100-125 mg/dL); WHO criteria 6.1-6.9 mmol/dL (100-125 mg/dL); IGT: oGTT 7.8-11.0 mmol/L (140-199 mg/dL). F BGL: Fasting blood glucose level; R BGL: Random blood glucose level; oGTT: 2-h oral glucose tolerance test.