Type 1 diabetes and polyglandular autoimmune syndrome: A review

doi:10.4239/wjd.v6.i1.67

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Diabetes. Feb 15, 2015; 6(1): 67-79
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.67

Table 4 Odds ratio of susceptibility genes for autoimmune endocrinopathies[117,144-160]

	T1D	HT	GD	AD
HLA-DR3	3.5	3.7	2-4	5
MICA	1.6	2.5	2	7
PTPN22	1.8	1.6	1.6	1.5
CTLA-4	1.5	5	1.5	1.8

AD: Addison’s disease; CTLA-4: Cytotoxic T lymphocyte antigen 4; GD: Graves’ disease; HLA: Human leukocyte antigen; HT: Hashimoto’s thyroiditis; MICA: MHC class I polypeptide-related sequence A; PTPN22: Protein tyrosine phosphatase non-receptor type 22; T1D: Type 1 diabetes.

Citation: Hansen MP, Matheis N, Kahaly GJ. Type 1 diabetes and polyglandular autoimmune syndrome: A review. World J Diabetes 2015; 6(1): 67-79
URL: https://www.wjgnet.com/1948-9358/full/v6/i1/67.htm
DOI: https://dx.doi.org/10.4239/wjd.v6.i1.67