Review
Copyright ©The Author(s) 2015.
World J Diabetes. Feb 15, 2015; 6(1): 151-166
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.151
Table 2 List of SNPs found in the genes of adiponectin pathway in metabolic disorders such as type 2 diabetes, obesity, dyslipidemia and cardiovascular disorders (coursey to http://www.genecards.org/ for providing the information regarding SNP loacation)
Ref.GeneSL No.LocationVariationSNP ID
Blech et al[96]PPARγ1Intron 1Pro12Alars1801282
Blech et al[96]; Ramya et al[81]ADIPOQ1 2 3 4 5 6 7 8 95’ flanking region Intron 1 Intron 1 Intron 1 Exon 1 coding synonymous Intron 1 Intron 1 5’ flanking region Exon 3 splicing enhancers−11365 C/G -4522 C/T -3971 A/G +276 G/T +45 T/G +349 A/G +712 G/A -11391 G/A Y111H T/Crs266729 rs822393 rs822396 rs1501299 rs2241766 rs2241767 rs3774261 rs17300539 rs17366743
Wang et al[97]ADIPOR11 2 3 4Intron 1 Intron 1 Intron 1 5’ transcription factor binding site+5646 A/G +5843 A/G -101 T/G -8503C/Trs1342386 rs1342387 rs2275737 rs6666089
Vaxillaire et al[98]ADIPOR21 2 3 4 5 6Exon 3 splicing enhancers Intron 1 5’ flanking region Intron 1 Intron 1 Intron 1+33371 C/T +26314 A/G -64241 T/G +8645 G/C +14645 A/T -35361 G/Ars12342 rs767870 rs1029629 rs1468491 rs4766415 rs10773982
Thameem et al[99]eNOS/NOS31 2Exon 3 splicing enhancers Intron 1Glu298Asp -786 T/Crs1799983 rs2070744
Zhang et al[100]NF-kB15’ flanking region-94 insertion/deletionrs28362491
Rees et al[101]PEPCK15’ flanking region-232C/Grs2071023
Jang et al[82] and Ferreira et al[83]Apolipoprotein A5 gene (APOA5)15’ flanking region-1131T/Crs662799
Ol et al[102]COX-215’ flanking region-765G/Crs20417
Ho et al[103]IL415’ flanking region-590 C/Trs2243250