Review
Copyright ©2014 Baishideng Publishing Group Inc.
World J Diabetes. Oct 15, 2014; 5(5): 651-658
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.651
Table 1 Use of metformin in chronic kidney disease
eGFR (mL/min per 1.73 m2)Use of metformin
> 60 (CKD 1 and 2)No contraindication
Check of renal function annually
45-60 (CKD 3a)Use of metformin-reduce dose (no more than 1.5-2 g daily)
Frequent check of renal function (every 3-6 mo)
30-45 (CKD 3b)Reduce dose (no more than 1-1.5 g daily)
No new cases
Frequent check of renal function (every 3-6 mo)
< 30 (CKD 4 and 5)Stop metformin