Emerging role of protein kinase C in energy homeostasis: A brief overview

Figure 1 Domain composition of protein kinase C-β and its regulation at the transcriptional and posttranscriptional levels. A: Membrane-targeting modules (C1 and C2), pleckstrin homology domain, the pseudosubstrate region, the kinase core and the C-terminal tail; B: Schematic representation of promoter structure of protein kinase C-β gene. Approximate locations of known regulatory regions are indicated. ATP: Adenosine-5’-triphosphate; PHLPP: PH domain and leucine rich repeat protein phosphatases; PDK-1: 3-phosphoinositide-dependent protein kinase 1.