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World J Diabetes. Apr 15, 2014; 5(2): 128-140
Published online Apr 15, 2014. doi: 10.4239/wjd.v5.i2.128
Published online Apr 15, 2014. doi: 10.4239/wjd.v5.i2.128
Figure 1 Overview of the pathogenic factors underlying development of type 2 diabetes mellitus.
As a complex disease, T2DM is caused by a combination of genetic, environmental and lifestyle factors, all of which interact together to produce insulin resistance and β-cell dysfunction, leading to hyperglycemia, which is the clinical hallmark of diabetes. FFA: Free fatty acids.T2DM: Type 2 diabetes mellitus.
- Citation: Brunetti A, Chiefari E, Foti D. Recent advances in the molecular genetics of type 2 diabetes mellitus. World J Diabetes 2014; 5(2): 128-140
- URL: https://www.wjgnet.com/1948-9358/full/v5/i2/128.htm
- DOI: https://dx.doi.org/10.4239/wjd.v5.i2.128