Starting glargine in insulin-naïve type 2 diabetic patients based on body mass index is safe

Table 3 Treatment efficacy data n (%)

	LANMET	LANMET PLUS	DeGold	DeGold PLUS
Initial insulin dose (U)	10.0 ± 0	10.0 ± 0	21.0 ± 7.3	18.3 ± 7.0
Initial insulin dose (U/kg)	0.13 ± 0.02	0.13 ± 0.03	0.26 ± 0.05	0.25 ± 0.05
Final insulin dose (U)	41.65 ± 14.00	87.00 ± 26.87	54.68 ± 21.63	48.19 ± 38.50
Final insulin dose (U/kg)	0.54 ± 0.20	0.59% ± 0.27%	0.67% ± 0.24%	0.65% ± 0.52%
Baseline A1C	9.39% ± 1.67%	9.35% ± 1.34%	9.21% ± 1.30%	9.61% ± 1.69%
Final A1C	7.36% ± 1.32%	7.32% ± 0.67%	6.82% ± 0.70%	7.38% ± 0.95%
Reduction in A1C	2.02% ± 1.60%	2.02% ± 1.17%	2.48% ± 1.23%	2.23% ± 1.69%
Proportion of patients reaching FPG target	19/26 (73)	16/20 (80)	22/23 (95)	20/21 (95)
Proportion of patients reaching A1C ≤ 7.5%	17/26 (65)	13/20 (65)	20/23 (87)	13/21 (62)
Proportion of patients reaching A1C ≤ 7.0%	11/26 (42)	5/20 (25)	16/23 (69)	7/21 (33)
Duration of titration to reach FPG target (d)	28 ± 31	15 ± 19	22 ± 20	20 ± 17
Weight variation (kg)	0.276 ± 2.94	1.190 ± 2.430	0.954 ± 2.590	1.630 ± 2.500
Final FPG (mg/dL)	119.4 ± 36.2	109.0 ± 28.7	106.6 ± 18.0	107.6 ± 17.3

FPG: Fasting plasma glucose.